Is extended or continuous infusion of carbapenems the obvious solution to improve clinical outcomes and reduce mortality?
نویسندگان
چکیده
منابع مشابه
Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: a systematic review and meta-analysis.
We sought to study whether the better pharmacokinetic and pharmacodynamic (PK/PD) properties of carbapenems and piperacillin/tazobactam, when the duration of infusion is longer, were associated with lower mortality. PubMed and Scopus were searched for studies reporting on patients treated with extended (≥3 hours) or continuous (24 hours) versus short-term duration (20-60 minutes) infusions of c...
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OBJECTIVES A better dosing strategy can improve clinical outcomes for patients. We sought to compare the extended or continuous infusion with conventional intermittent infusion of piperacillin/tazobactam, investigating which approach is better and worthy of recommendation for clinical use. METHODS Articles were gathered from PubMed, Web of Science, ProQuest, Science Direct, Cochrane, two Chin...
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ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 57 2 شماره
صفحات -
تاریخ انتشار 2013